WinRS Breakfast/Subcommittee Meeting – 7:00AM-8:00AM
Topic: “Overcoming Impostor Syndrome”
Panelist:
Dr. Zelieann Craig
University of Arizona
Dr. Ping Xia
Johns Hopkins School of Medicine

Dr. Kate Loveland
Hudson Institute of Medical Research

Dr. Janice Bailey
Scientific Director
Québec Research Funds for Nature and Technologies

Poster Session B – 8:00AM-10:00AM
Flash Talks C – 8:00AM -8:40AM
Flash Talks D – 8:00AM -8:40AM
Break – 10:00AM – 10:30AM
Focus Sessions AM - 10:30AM-12:00PM
Session 6 - Placental Adaptations to Adversity
Senior Co-Chair: Alina Maloyan, Oregon Health Sciences University, USA
Trainee Co-Chair: Rachel West, Colorado Center for Reproductive Medicine, USA
Understanding Placental Adaptation to Maternal Malnutrition. Michael Satterfield, Texas A&M University, USA
Morphological and Epigenetic Abnormalities in the Placenta Linked to Embryo Culture in a Mouse Model of In Vitro Fertilization. Lisa Vrooman, Eric A. Rhon-Calderon, Olivia Y. Chao, Duy Nguyen, Laren Riesche, Richard M. Schultz, Marisa S. Bartolomei
Protective Role of Il33 On Negative Pregnancy Outcomes Associated with Lipopolysaccharide Exposure. Keisuke Kozai, Khursheed Iqbal, Regan L. Scott, Pramod Dhakal, Michael J. Soares
Society for Reproductive Biology-SSR Exchange Lecture: New Diagnostics for Pregnancy Complications. Tu'uhevah Kaitu’u-Lino, The University of Melbourne, Australia
Session 7 - Reproductive Aging
Senior Co-Chair: Francesca Duncan, Northwestern University, USA
Trainee Co-Chair: Kathryn Grive, Cornell University, USA
Developmental Mechanisms for Protracted Female Fertility: Insights from the Naked Mole-Rat. Ned Place, Cornell University, USA
Increased Expression of Kifc1 And Kifc5b Targeting Endogenous-Sirna Contribute to The Age-Related Decline in Oocyte Quality. Bettina Mihalas, Nicole J. Camlin, Miguel J. Xavier, Alexandra E. Peters, Janet E. Holt; Jessie M. Sutherland, Eileen A. Mclaughlin, Andrew L. Eamens, Brett Nixon
The Telomere Length of Spermatozoa as An Epigenetic Biomarker of Sperm Quality and Aging. Mingju Cao, Peter Chan, Marie-Claude Léveillé, Bernard Robaire
The Conversion of a Homeostatic to Reactive Matrix: Hyaluronan And The Aging Ovarian Stroma. Michele Pritchard, University of Kansas Medical Center, USA
Session 8 - Editing the Germ Line and Genome
Senior Co-Chair: Joao Ramalho-Santos, University of Coimbra, Portugal
Trainee Co-Chair: Saniya Rattan, University of Illinois at Urbana-Champaign
How CRISPR/Cas9 'Gene Drive' Technology in Laboratory Mice Could Make the Impossible Possible. Kimberly Cooper, University of California San Diego, USA
In Utero Imaging of Clock Gene Expression Reveals the Development of the Circadian Clock. Keenan Bates, Ron McCarthy, Tatiana Simon, Jacob Amme, Sarah England, Erik Harzog
A Genetic Toolbox for Functional In Vivo And Structural in Situ Analysis of the Mouse Testis. David Fleck, Naofumi Uesaka, Justine Fischoeder, Lina Kenzler, Jennifer Spehr, Marc Spehr
Editing the Non-Human Primate Genome. Erika Sasaki, Keio University School of Medicine, Japan
Session 9 - Becoming Haploid
Senior Co-Chair: Andy Childs, Imperial College London, UK
Trainee Co-Chair: Brittany Croft, Murdoch Children’s Research Institute, Australia
Molecular and Evolutionary Strategies of Meiotic Cheating by Selfish Elements. Takashi Akera, University of Pennsylvania, USA
Control of Anaphase Onset in Mammalian Female Meiosis I. Lenka Radonova, Michal Skultety, Kristina Kovacovicova, Jaroslava Sebestova, Thang Quang Dang-Nguyen, Michael Hopkins, Bela Novak, Martin Anger
Interplay Between Caspase 9 And X-Linked Cellular Inhibitor of Apoptosis Protein (XIAP) In the Elimination of Mouse Oocytes During Fetal and Neonatal Ovarian Development. Xueqing Liu, Fatima EI Mansouri, Teruko Taketo
Phenotypic Variation in Female Reproductive Parameters in Genetically Diverse Mice: A Window to Understand Human Infertility. Ewelina Bolcun-Filas, Jackson Laboratory, USA
Session 10 - The Virendra B. Mahesh Neuroendocrine Session: Neuroendocrine Control of Metabolism
Senior Co-Chair: Djurdjica Coss, University of California Riverside, USA
Trainee Co-Chair: Heather Talbott, Oregon National Primate Research Center, USA
Conflicting Desires: A POMC Switch for Breeding and Feeding. Jennifer Hill, University of Toledo, USA
Translational Control in The Gonadotrope: Musashi Mediates Crosstalk Between Metabolism and Reproduction. Ana Rita Silva Moreira, Tiffany K. Miles, Anessa Haney, Linda Hardy, Melody L. Allensworth, Michael G. Kharas, Christopher J. Lengner, Melanie C. MacNicol, Angus M. MacNicol, Gwen V. Childs, Angela K. Odle
Gonadotrope-Specific Acvr2a and Acvr2b Conditional Knockout Animals Are Hypogonadal and Fsh-Deficient. Gauthier Schang, Luisina Ongaro, Ulrich Boehm, Se-Jin Lee, Daniel Bernard
Dissecting the Brain Mechanisms Underpinning PCOS. Rebecca Campbell, University of Otago, New Zealand
Break – 12:00PM-1:30PM
Trainee Mentor Lunch - 12:15PM-1:15PM
Focus Session PM - 1:30PM-3:00PM
Session 11 - Signals Regulating Implantation
Senior Co-Chair: Indrani Bagchi, University of Illinois Urbana-Champaign, USA
Trainee Co-Chair: Riley Thompson, University of Tennessee, USA
Comparative Insights into How Uterine Glands Function in Pregnancy Establishment. Tom Spencer, University of Missouri, USA
WNK1 in the Uterus: A Previously Undescribed Role in Implantation. Ru-pin Alicia Chi, Nyssa Adams, San-pin Wu Chou-long Huang, John Lydon, Francesco DeMayo
Intrauterine Inhibition of Chemokine Receptor 4 Signaling Modulates Local and Systemic Inflammation in Ovine Pregnancy. Stacia McIntosh, Clara Maxam, Marlie Maestas, Kelsey Quinn, Ryan Ashley
Embryo-Maternal Interaction Prior To Implantation in Cattle. Pat Lonergan, University College Dublin, Ireland
Session 12 - The John J. Eppig Session: Modulation of Oocyte Growth
Senior Co-Chair: Richard Schultz, University of California Davis, USA
Trainee Co-Chair: Kelsey Brooks, Oregon National Primate Research Center, USA
Wrestling with Reproduction: The Critical Roles of Protein Sumoylation In Oocyte Development. Stephanie Pangas, PhD, Baylor College, USA
The Orphan Nuclear Receptor Nr5a2 Regulates Primordial Follicle Activation. Marie-Charlotte Meinsohn, Anthony Estienne, H. Duygu Saatcioglu, David Pepin, Bruce D. Murphy
Tgfβ/Smad Signaling Regulates Transzonal Projection (Tzp) Formation in Growing Follicles of The Mouse Ovary. Sofia Granados-Aparici, Qin Yang, Hugh Clarke
Post-Transcriptional Regulation of Germ Cell Development. Guang Hu, National Institute of Environmental Health Sciences, USA
Session 13 - Genomic Insights into Reproductive Success
Senior Co-Chair: Folami Ideraabdullah, University of North Carolina – Chapel Hill, USA
Trainee Co-Chair: Benjamin Duran, Ohio State University, USA
Genomic Insights into Reproductive Success. Pierre Ray, CHU-Grenoble Alpes, France
Dynamic Evolution of Male Fertility Genes in Humans and Other Great Apes. Marta Tomaszkiewicz, Arslan A. Zaidi, Danling Ye, Kristoffer Sahlin, Rahul Vegesna, Paul Medvedev, Kate Anthony, Corey Liebowitz, Michael DeGiorgio, Mark D. Shriver, Kateryna D. Makova
Integrated Epigenome, Exome and Transcriptome Analyses Reveal Molecular Subtypes and Suggest Homeotic Transformation in Uterine Fibroids. Jitu George, Huihui Fan, Benjamin Johnson, Anindita Chatterjee, Amanda L. Patterson, Julie Koewitz, Marie Adams, Zachary Madaj, Hui Shen, Jose M. Teixeira
Genes and Mechanism of Androgenetic Hydatidiform Moles: An Answer to A 40-Year Old Question. Rima Slim, McGill University, Canada
Session 14 - In and Out of the Testis Through the Blood-Testis Barrier
Senior Co-Chair: Jannette Dufour, Texas Tech University Health Science Center, USA
Trainee Co-Chair: Jess Dunleavy, Monash University, Australia
Sperm and Cancer/Testis Antigens Egress Mouse Testes to Maintain Immune Protection. Kenneth Tung, University of Virginia, USA
ATP-Induced Calcium Signals and Contractions in Testicular Peritubular Cells. Lina Kenzler, David Fleck, Nadine Mundt, Robert Moosmann, Jennifer Spehr, Marc Spehr
The Role of ECM in Testicular Organoid Development. Maxwell Edmonds, Hanna Pulaski, Kyle E. Orwig, Teresa K. Woodruff
Use of Endogenously Produced BTB Modifiers to Enhance Efficacy of Non-Hormonal Male Contraceptives. C. Yan Cheng, Population Council, USA
Session 15 - Alternative Instructions: Rewiring Reproductive Cancers
Senior Co-Chair: Kanako Hayashi, Southern Illinois University School of Medicine, USA
Trainee Co-Chair: Fei Zhao, National Institute of Environmental Health Sciences, USA
Epigenetic Rewiring of Ovarian Cancer for Cancer Therapy. Ken Nephew, Indiana University, USA
Anti-apoptotic Based Fertoprotective Agents do not Protect the Ovarian Stroma from Radiation-induced Fibrosis in the Nonhuman Primate. Sharrón Manuel, Mary B. Zelinski, Brian W. Johnson, Megan J. Larmore, Michele T. Pritchard, Francesca E. Duncan
TGFbeta is Critical for Stromal and Epithelial Paracrine Signaling in Endometrial Cancer. Diana Monsivais, Maya L. Kriseman, Julio Agno, Ramya Masand, Chad Creighton, Martin M. Matzuk
Tackling Endometrial Cancer: A New Frontier, Julie Kim, Northwestern University, USA
Break – 3:00PM – 3:30PM
Plenary Session – 3:30PM-5:30PM
Keynote Speaker:
Gavin Kelsey, PhD
The Babraham Institute, UK

Lecture: “Single-Cell Sequencing Reveals Genetic and Dietary Influences On The Oocyte Epigenome”
SSR Research Award
2019 Recipient
Humphrey Yao, PhD
Principal Investigator
NIEHS/NIH
Reproductive Developmental Biology Lab

Jansen SSR Distinguish Service Award
2019 Recipient
Sally Perreault Darney, PhD
Editor-in-Chief
Environmental Health Perspectives
NIEHS

Keynote Speaker:
Kathy Niakan, PhD
The Francis Crick Institute, UK

Lecture: “Regulation of Differentiation During Human Preimplantation Embryo Development”